Y24N (p.Tyr24Asn) variant of ABL1 (Tyrosine-protein kinase ABL1)
Y24N (p.Tyr24Asn) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
Y24N (p.Tyr24Asn) variant details
- p.Tyr24Asn
- gnomAD 9-130835516-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.466
- REVEL 0.42
- MetaLR 0.28
- MetaSVM -0.59
- CADD 21.90
- PolyPhen-2 0.99
- SIFT 0.26
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available