S35L (p.Ser35Leu) variant of ABL1 (Tyrosine-protein kinase ABL1)
S35L (p.Ser35Leu) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
S35L (p.Ser35Leu) variant details
- p.Ser35Leu
- gnomAD 9-130714411-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.62
- MetaLR 0.29
- MetaSVM -0.72
- CADD 22.70
- SIFT 0.10
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available