S35A (p.Ser35Ala) variant of ABL1 (Tyrosine-protein kinase ABL1)
S35A (p.Ser35Ala) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
S35A (p.Ser35Ala) variant details
- p.Ser35Ala
- gnomAD 9-130854087-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.12
- MetaLR 0.07
- MetaSVM -1.08
- CADD 23.10
- PolyPhen-2 0.62
- SIFT 0.65
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available
- Literature evidence available