S22R (p.Ser22Arg) variant of ABL1 (Tyrosine-protein kinase ABL1)
S22R (p.Ser22Arg) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
S22R (p.Ser22Arg) variant details
- p.Ser22Arg
- gnomAD 9-130835510-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.438
- REVEL 0.39
- MetaLR 0.18
- MetaSVM -0.94
- CADD 21.50
- PolyPhen-2 0.19
- SIFT 0.52
- Population evidence available
- Structural context available
- Literature evidence available