S21Y (p.Ser21Tyr) variant of ABL1 (Tyrosine-protein kinase ABL1)
S21Y (p.Ser21Tyr) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
S21Y (p.Ser21Tyr) variant details
- p.Ser21Tyr
- gnomAD 9-130835508-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.494
- REVEL 0.38
- MetaLR 0.35
- MetaSVM -0.18
- CADD 21.10
- PolyPhen-2 0.99
- SIFT 0.88
- Population evidence available
- Structural context available
- Literature evidence available