S21F (p.Ser21Phe) variant of ABL1 (Tyrosine-protein kinase ABL1)
S21F (p.Ser21Phe) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
S21F (p.Ser21Phe) variant details
- p.Ser21Phe
- gnomAD 9-130835508-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.486
- REVEL 0.35
- MetaLR 0.35
- MetaSVM -0.19
- CADD 21.60
- PolyPhen-2 0.99
- SIFT 0.62
- Population evidence available
- Structural context available
- Literature evidence available