S20Y (p.Ser20Tyr) variant of ABL1 (Tyrosine-protein kinase ABL1)
S20Y (p.Ser20Tyr) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
S20Y (p.Ser20Tyr) variant details
- p.Ser20Tyr
- gnomAD 9-130835505-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.381
- REVEL 0.19
- MetaLR 0.21
- MetaSVM -0.69
- CADD 19.60
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available