S18Y (p.Ser18Tyr) variant of ABL1 (Tyrosine-protein kinase ABL1)
S18Y (p.Ser18Tyr) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
S18Y (p.Ser18Tyr) variant details
- p.Ser18Tyr
- gnomAD 9-130835499-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.49
- REVEL 0.37
- MetaLR 0.35
- MetaSVM -0.20
- CADD 21.30
- PolyPhen-2 0.99
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available