L8M (p.Leu8Met) variant of ABL1 (Tyrosine-protein kinase ABL1)
L8M (p.Leu8Met) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
L8M (p.Leu8Met) variant details
- p.Leu8Met
- gnomAD 9-130835468-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.39
- MetaLR 0.37
- MetaSVM -0.61
- CADD 16.50
- PolyPhen-2 0.99
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available