L6M (p.Leu6Met) variant of ABL1 (Tyrosine-protein kinase ABL1)
L6M (p.Leu6Met) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
L6M (p.Leu6Met) variant details
- p.Leu6Met
- gnomAD 9-130835462-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.35
- MetaLR 0.38
- MetaSVM -0.65
- CADD 16.60
- PolyPhen-2 0.99
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available