L2M (p.Leu2Met) variant of ABL1 (Tyrosine-protein kinase ABL1)
L2M (p.Leu2Met) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
L2M (p.Leu2Met) variant details
- p.Leu2Met
- gnomAD rs1479537095
- Missense
- Variant Prioritization Score for Impact Estimate 0.428
- REVEL 0.38
- MetaLR 0.25
- MetaSVM -0.63
- CADD 20.60
- PolyPhen-2 0.35
- SIFT 0.01
- Population evidence available
- Structural context available