L25Q (p.Leu25Gln) variant of ABL1 (Tyrosine-protein kinase ABL1)
L25Q (p.Leu25Gln) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
L25Q (p.Leu25Gln) variant details
- p.Leu25Gln
- gnomAD 9-130835520-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.463
- REVEL 0.42
- MetaLR 0.24
- MetaSVM -0.65
- CADD 22.00
- PolyPhen-2 0.53
- SIFT 0.22
- Population evidence available
- Structural context available
- Literature evidence available