L25M (p.Leu25Met) variant of ABL1 (Tyrosine-protein kinase ABL1)
L25M (p.Leu25Met) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
L25M (p.Leu25Met) variant details
- p.Leu25Met
- gnomAD 9-130835519-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.20
- MetaLR 0.21
- MetaSVM -0.89
- CADD 19.80
- PolyPhen-2 0.07
- SIFT 0.19
- Population evidence available
- Structural context available
- Literature evidence available