L17M (p.Leu17Met) variant of ABL1 (Tyrosine-protein kinase ABL1)
L17M (p.Leu17Met) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
L17M (p.Leu17Met) variant details
- p.Leu17Met
- Ensembl rs2132913402
- Missense
- Variant Prioritization Score for Impact Estimate 0.451
- REVEL 0.28
- MetaLR 0.37
- MetaSVM -0.23
- CADD 21.20
- PolyPhen-2 0.99
- SIFT 0.19
- Population evidence available
- Structural context available