K15R (p.Lys15Arg) variant of ABL1 (Tyrosine-protein kinase ABL1)
K15R (p.Lys15Arg) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
K15R (p.Lys15Arg) variant details
- p.Lys15Arg
- gnomAD 9-130835490-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- REVEL 0.30
- MetaLR 0.30
- MetaSVM -0.51
- CADD 22.30
- PolyPhen-2 0.96
- SIFT 0.22
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available