K14T (p.Lys14Thr) variant of ABL1 (Tyrosine-protein kinase ABL1)
K14T (p.Lys14Thr) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
K14T (p.Lys14Thr) variant details
- p.Lys14Thr
- gnomAD 9-130835487-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.43
- REVEL 0.34
- MetaLR 0.31
- MetaSVM -0.49
- CADD 22.10
- PolyPhen-2 0.98
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available