K14R (p.Lys14Arg) variant of ABL1 (Tyrosine-protein kinase ABL1)
K14R (p.Lys14Arg) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
K14R (p.Lys14Arg) variant details
- p.Lys14Arg
- gnomAD 9-130835487-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.403
- REVEL 0.29
- MetaLR 0.29
- MetaSVM -0.59
- CADD 22.20
- PolyPhen-2 0.96
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available