K14M (p.Lys14Met) variant of ABL1 (Tyrosine-protein kinase ABL1)
K14M (p.Lys14Met) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
K14M (p.Lys14Met) variant details
- p.Lys14Met
- gnomAD 9-130835487-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.449
- REVEL 0.38
- MetaLR 0.33
- MetaSVM -0.29
- CADD 22.00
- PolyPhen-2 0.99
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available