C23S (p.Cys23Ser) variant of ABL1 (Tyrosine-protein kinase ABL1)
C23S (p.Cys23Ser) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
C23S (p.Cys23Ser) variant details
- p.Cys23Ser
- gnomAD 9-130835514-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.389
- REVEL 0.28
- MetaLR 0.15
- MetaSVM -0.93
- CADD 21.50
- PolyPhen-2 0.01
- SIFT 0.28
- Population evidence available
- Structural context available
- Literature evidence available