C11S (p.Cys11Ser) variant of ABL1 (Tyrosine-protein kinase ABL1)
C11S (p.Cys11Ser) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
C11S (p.Cys11Ser) variant details
- p.Cys11Ser
- gnomAD 9-130835477-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.525
- REVEL 0.53
- MetaLR 0.35
- MetaSVM -0.33
- CADD 21.90
- PolyPhen-2 0.95
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available