A34T (p.Ala34Thr) variant of ABL1 (Tyrosine-protein kinase ABL1)
A34T (p.Ala34Thr) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
A34T (p.Ala34Thr) variant details
- p.Ala34Thr
- gnomAD 9-130854084-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.22
- REVEL 0.05
- MetaLR 0.06
- MetaSVM -1.07
- CADD 22.20
- PolyPhen-2 0.21
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available