A34P (p.Ala34Pro) variant of ABL1 (Tyrosine-protein kinase ABL1)
A34P (p.Ala34Pro) in ABL1 (Tyrosine-protein kinase ABL1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
A34P (p.Ala34Pro) variant details
- p.Ala34Pro
- cosmic curated COSV59330
- Missense
- Variant Prioritization Score for Impact Estimate 0.284
- REVEL 0.16
- MetaLR 0.09
- MetaSVM -1.06
- CADD 22.30
- PolyPhen-2 0.71
- SIFT 0.04
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available