T135M (p.Thr135Met) variant of ABCG2 (Q9UNQ0)
T135M (p.Thr135Met) in ABCG2 (Q9UNQ0) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
T135M (p.Thr135Met) variant details
- p.Thr135Met
- cosmic curated COSV99419
- ExAC rs770985871
- gnomAD rs770985871
- Missense
- Variant Prioritization Score for Impact Estimate 0.725
- REVEL 0.69
- CADD 26.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 0.00039)
- Structural context available