P11L (p.Pro11Leu) variant of ABCG2 (Q9UNQ0)
P11L (p.Pro11Leu) in ABCG2 (Q9UNQ0) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
P11L (p.Pro11Leu) variant details
- p.Pro11Leu
- gnomAD rs930748886
- Missense
- Variant Prioritization Score for Impact Estimate 0.386
- REVEL 0.31
- CADD 22.20
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available