L28P (p.Leu28Pro) variant of ABCG2 (Q9UNQ0)
L28P (p.Leu28Pro) in ABCG2 (Q9UNQ0) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
L28P (p.Leu28Pro) variant details
- p.Leu28Pro
- TOPMed rs1425581427
- gnomAD rs1425581427
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.20
- CADD 0.93
- PolyPhen-2 0.00
- SIFT 0.34
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available