L140F (p.Leu140Phe) variant of ABCG2 (Q9UNQ0)
L140F (p.Leu140Phe) in ABCG2 (Q9UNQ0) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
L140F (p.Leu140Phe) variant details
- p.Leu140Phe
- TOPMed rs1724843141
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.25
- CADD 21.40
- PolyPhen-2 0.77
- SIFT 0.16
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available