G74V (p.Gly74Val) variant of ABCG2 (Q9UNQ0)
G74V (p.Gly74Val) in ABCG2 (Q9UNQ0) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data and structural context.
G74V (p.Gly74Val) variant details
- p.Gly74Val
- ExAC rs199976573
- TOPMed rs199976573
- gnomAD rs199976573
- Missense
- Variant Prioritization Score for Impact Estimate 0.85
- REVEL 0.91
- CADD 25.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available