G74S (p.Gly74Ser) variant of ABCG2 (Q9UNQ0)
G74S (p.Gly74Ser) in ABCG2 (Q9UNQ0) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data and structural context.
G74S (p.Gly74Ser) variant details
- p.Gly74Ser
- TOPMed rs1397059546
- gnomAD rs1397059546
- Missense
- Variant Prioritization Score for Impact Estimate 0.863
- REVEL 0.91
- CADD 29.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available