G74D (p.Gly74Asp) variant of ABCG2 (Q9UNQ0)
G74D (p.Gly74Asp) in ABCG2 (Q9UNQ0) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data and structural context.
G74D (p.Gly74Asp) variant details
- p.Gly74Asp
- ExAC rs199976573
- TOPMed rs199976573
- gnomAD rs199976573
- Missense
- Variant Prioritization Score for Impact Estimate 0.828
- REVEL 0.87
- CADD 25.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 0.0002)
- Structural context available