A149P (p.Ala149Pro) variant of ABCG2 (Q9UNQ0)
A149P (p.Ala149Pro) in ABCG2 (Q9UNQ0) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
A149P (p.Ala149Pro) variant details
- p.Ala149Pro
- 1000Genomes rs201006821
- ExAC rs201006821
- TOPMed rs201006821
- gnomAD rs201006821
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.12
- CADD 18.60
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the 1KG:JPT population (allele frequency 0.0049)
- Structural context available