A145P (p.Ala145Pro) variant of ABCG2 (Q9UNQ0)
A145P (p.Ala145Pro) in ABCG2 (Q9UNQ0) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
A145P (p.Ala145Pro) variant details
- p.Ala145Pro
- TOPMed rs947226023
- gnomAD rs947226023
- Missense
- Variant Prioritization Score for Impact Estimate 0.496
- REVEL 0.28
- CADD 26.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available