C26W (p.Cys26Trp) variant of ABCC8 (Q09428)
C26W (p.Cys26Trp) in ABCC8 (Q09428) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
C26W (p.Cys26Trp) variant details
- p.Cys26Trp
- gnomAD rs1263713686
- Missense
- Variant Prioritization Score for Impact Estimate 0.756
- REVEL 0.88
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 5.7e-05)
- Structural context available