Y65C (p.Tyr65Cys) variant of ABCC2 (Q92887)
Y65C (p.Tyr65Cys) in ABCC2 (Q92887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
Y65C (p.Tyr65Cys) variant details
- p.Tyr65Cys
- ExAC rs766200636
- TOPMed rs766200636
- gnomAD rs766200636
- Missense
- Variant Prioritization Score for Impact Estimate 0.538
- CADD 24.60
- PolyPhen-2 0.94
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available