P36L (p.Pro36Leu) variant of ABCC2 (Q92887)
P36L (p.Pro36Leu) in ABCC2 (Q92887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
P36L (p.Pro36Leu) variant details
- p.Pro36Leu
- ESP rs368821808
- ExAC rs368821808
- TOPMed rs368821808
- gnomAD rs368821808
- Missense
- Variant Prioritization Score for Impact Estimate 0.796
- CADD 27.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 9.7e-05)
- Structural context available