L76P (p.Leu76Pro) variant of ABCC2 (Q92887)
L76P (p.Leu76Pro) in ABCC2 (Q92887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
L76P (p.Leu76Pro) variant details
- p.Leu76Pro
- gnomAD rs1229176388
- Missense
- Variant Prioritization Score for Impact Estimate 0.658
- CADD 28.50
- PolyPhen-2 0.72
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available