L37W (p.Leu37Trp) variant of ABCC2 (Q92887)
L37W (p.Leu37Trp) in ABCC2 (Q92887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
L37W (p.Leu37Trp) variant details
- p.Leu37Trp
- gnomAD 10-99784684-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.569
- CADD 28.70
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available