L37F (p.Leu37Phe) variant of ABCC2 (Q92887)
L37F (p.Leu37Phe) in ABCC2 (Q92887) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
L37F (p.Leu37Phe) variant details
- p.Leu37Phe
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.512
- CADD 25.80
- PolyPhen-2 0.91
- SIFT 0.01
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available