K63T (p.Lys63Thr) variant of ABCC2 (Q92887)
K63T (p.Lys63Thr) in ABCC2 (Q92887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
K63T (p.Lys63Thr) variant details
- p.Lys63Thr
- gnomAD 10-99784762-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- CADD 18.10
- PolyPhen-2 0.01
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available