I77V (p.Ile77Val) variant of ABCC2 (Q92887)
I77V (p.Ile77Val) in ABCC2 (Q92887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
I77V (p.Ile77Val) variant details
- p.Ile77Val
- ExAC rs763168977
- gnomAD rs763168977
- Missense
- Variant Prioritization Score for Impact Estimate 0.48
- CADD 16.40
- PolyPhen-2 0.00
- SIFT 0.34
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available