D22A (p.Asp22Ala) variant of ABCC2 (Q92887)
D22A (p.Asp22Ala) in ABCC2 (Q92887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
D22A (p.Asp22Ala) variant details
- p.Asp22Ala
- cosmic curated COSV64971
- ExAC rs769292618
- TOPMed rs769292618
- gnomAD rs769292618
- Missense
- Variant Prioritization Score for Impact Estimate 0.669
- CADD 29.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 0.0034)
- Structural context available