C6Y (p.Cys6Tyr) variant of ABCC2 (Q92887)
C6Y (p.Cys6Tyr) in ABCC2 (Q92887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
C6Y (p.Cys6Tyr) variant details
- p.Cys6Tyr
- ExAC rs769004636
- gnomAD rs769004636
- Missense
- Variant Prioritization Score for Impact Estimate 0.739
- CADD 24.50
- PolyPhen-2 0.16
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.7e-05)
- Structural context available