T21M (p.Thr21Met) variant of ABCC1 (P33527)
T21M (p.Thr21Met) in ABCC1 (P33527) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
T21M (p.Thr21Met) variant details
- p.Thr21Met
- rs762542019
- ExAC rs762542019
- gnomAD rs762542019
- NCI-TCGA Cosmic COSV1005
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.494
- REVEL 0.29
- CADD 24.70
- PolyPhen-2 0.86
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available