Y114F (p.Tyr114Phe) variant of ABCB1 (ATP-dependent translocase ABCB1)
Y114F (p.Tyr114Phe) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
Y114F (p.Tyr114Phe) variant details
- p.Tyr114Phe
- ESP rs374713722
- ExAC rs374713722
- TOPMed rs374713722
- gnomAD rs374713722
- Missense
- Variant Prioritization Score for Impact Estimate 0.612
- CADD 22.80
- PolyPhen-2 1.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available