V34G (p.Val34Gly) variant of ABCB1 (ATP-dependent translocase ABCB1)
V34G (p.Val34Gly) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as drug response in the context of Tramadol response. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes structural context.
V34G (p.Val34Gly) variant details
- p.Val34Gly
- rs1584911161
- ClinGen CA368094129
- ClinVar RCV001028459
- Ensembl rs1584911161
- drug response
- Tramadol response
- Missense
- Variant Prioritization Score for Impact Estimate 0.558
- AlphaMissense 0.57
- MetaLR 0.52
- MetaSVM 0.13
- PolyPhen-2 0.64
- SIFT 0.00
- MutPred 0.43
- ClinVar: drug response (Tramadol response)
- EBI: Drug response
- UniProt: Drug response
- Structural context available