T76I (p.Thr76Ile) variant of ABCB1 (ATP-dependent translocase ABCB1)
T76I (p.Thr76Ile) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
T76I (p.Thr76Ile) variant details
- p.Thr76Ile
- Ensembl rs200177995
- Missense
- Variant Prioritization Score for Impact Estimate 0.656
- CADD 23.00
- PolyPhen-2 0.99
- SIFT 0.12
- Most common in the HGDP:BANTUKENYA population (allele frequency 0.1)
- Structural context available