S90T (p.Ser90Thr) variant of ABCB1 (ATP-dependent translocase ABCB1)
S90T (p.Ser90Thr) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
S90T (p.Ser90Thr) variant details
- p.Ser90Thr
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.067
- CADD 0.00
- PolyPhen-2 0.01
- SIFT 0.63
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available