R7G (p.Arg7Gly) variant of ABCB1 (ATP-dependent translocase ABCB1)
R7G (p.Arg7Gly) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
R7G (p.Arg7Gly) variant details
- p.Arg7Gly
- ExAC rs758755760
- TOPMed rs758755760
- gnomAD rs758755760
- Missense
- Variant Prioritization Score for Impact Estimate 0.132
- CADD 10.20
- PolyPhen-2 0.00
- SIFT 0.17
- Most common in the Latino/Admixed American population (allele frequency 6.7e-05)
- Structural context available