P32R (p.Pro32Arg) variant of ABCB1 (ATP-dependent translocase ABCB1)
P32R (p.Pro32Arg) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
P32R (p.Pro32Arg) variant details
- p.Pro32Arg
- gnomAD rs1257107888
- Missense
- Variant Prioritization Score for Impact Estimate 0.638
- CADD 22.10
- PolyPhen-2 0.40
- SIFT 0.23
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available