M68V (p.Met68Val) variant of ABCB1 (ATP-dependent translocase ABCB1)
M68V (p.Met68Val) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
M68V (p.Met68Val) variant details
- p.Met68Val
- TOPMed rs865799545
- gnomAD rs865799545
- Missense
- Variant Prioritization Score for Impact Estimate 0.457
- CADD 17.70
- PolyPhen-2 0.29
- SIFT 0.12
- Most common in the African/African-American population (allele frequency 9.7e-05)
- Structural context available