M111V (p.Met111Val) variant of ABCB1 (ATP-dependent translocase ABCB1)
M111V (p.Met111Val) in ABCB1 (ATP-dependent translocase ABCB1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
M111V (p.Met111Val) variant details
- p.Met111Val
- ExAC rs761202837
- TOPMed rs761202837
- gnomAD rs761202837
- Missense
- Variant Prioritization Score for Impact Estimate 0.473
- CADD 20.00
- PolyPhen-2 0.01
- SIFT 0.04
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available